Assessing arsenic and selenium in a single nail clipping using portable X-ray fluorescence

dc.contributor.author Fleming,DEB en
dc.contributor.author Nader,MN en
dc.contributor.author Foran,KA en
dc.contributor.author Groskopf,C en
dc.contributor.author Reno,MC en
dc.contributor.author Ware,CS en
dc.contributor.author Tehrani,M en
dc.contributor.author Diana Filipa Guimarães en
dc.contributor.author Parsons,PJ en
dc.date.accessioned 2018-01-16T11:32:32Z
dc.date.available 2018-01-16T11:32:32Z
dc.date.issued 2017 en
dc.description.abstract The feasibility of measuring arsenic and selenium contents in a single nail clipping was investigated using a small-focus portable X-ray fluorescence (XRF) instrument with monochromatic excitation beams. Nail clipping phantoms supplemented with arsenic and selenium to produce materials with 0, 5, 10, 15, and 20 mu g/g were used for calibration purposes. In total, 10 different clippings were analyzed at two different measurement positions. Energy spectra were fit with detection peaks for arsenic K-alpha, selenium K-alpha, arsenic K-beta, selenium K-beta, and bromine K-alpha characteristic X-rays. Data analysis was performed under two distinct conditions of fitting constraint. Calibration lines were established from the amplitude of each of the arsenic and selenium peaks as a function of the elemental contents in the clippings. The slopes of the four calibration lines were consistent between the two conditions of analysis. The calculated minimum detection limit (MDL) of the method, when considering the Ka peak only, ranged from 0.210 +/- 0.002 mu g/g selenium under one condition of analysis to 0.777 +/- 0.009 mu g/g selenium under another. Compared with previous portable XRF nail clipping studies, MDLs were substantially improved for both arsenic and selenium. The new measurement technique had the additional benefits of being short in duration (similar to 3 min) and requiring only a single nail clipping. The mass of the individual clipping used did not appear to play a major role in signal strength, but positioning of the clipping is important. en
dc.identifier.uri http://repositorio.inesctec.pt/handle/123456789/6314
dc.identifier.uri http://dx.doi.org/10.1016/j.apradiso.2016.11.015 en
dc.language eng en
dc.relation 6888 en
dc.rights info:eu-repo/semantics/embargoedAccess en
dc.title Assessing arsenic and selenium in a single nail clipping using portable X-ray fluorescence en
dc.type article en
dc.type Publication en
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